Treatment of postoperative gastrointestinal dysfunction

Discussion Gastrointestinal function recovery is an important link to abdominal operations, especially operations on digestive tract and will directly influence the effect of abdominal operations [ 19 ].

Treatment of postoperative gastrointestinal dysfunction

Received Feb 6; Accepted May Abstract Background Practitioners of traditional Chinese medicine know that auricular point acupressure APP using vaccaria seeds on the large intestine point CO7 has a significant effect on postoperative gastrointestinal dysfunction.

A standardized, clinical, research design will transform this clinical experience into scientific evidence, thus providing a basis to promote the wider use of this therapy. We aim to carry out a double-blind, randomized, controlled trial RCT to evaluate the efficacy and safety of APP treatment for gastrointestinal dysfunction after laparoscopic cholecystectomy.

Study subjects are being selected from among hospitalized patients who have undergone laparoscopic cholecystectomy at the Department of Minimally Invasive Surgery Treatment of postoperative gastrointestinal dysfunction Tianjin Nankai Hospital.

A specifically appointed investigator will be responsible for the randomization. The APP therapy or sham stimulation will be performed 6 h after surgery and every 12 h subsequently; six sessions will be conducted, each lasting 3 min.

Background

The first evaluation will be performed immediately before the first treatment 6 h after surgery and, then, every 12 h for seven evaluations. The primary outcome is the time to first passage of flatus after surgery; the secondary outcome measures are abdominal distension, nausea, vomiting, time to first defecation, psychological status, and quality of life.

Discussion This pilot trial is a standardized, scientific, clinical trial designed to evaluate the efficacy and safety of APP treatment—using vaccaria seeds on CO7—for gastrointestinal dysfunction after laparoscopic cholecystectomy.

We aim to provide objective evidence to promote this therapy in clinical practice.

Mechanisms and Treatment of Postoperative Ileus | Surgery | JAMA Surgery | JAMA Network

Registered on 14 December Electronic supplementary material The online version of this article doi: Abdominal pain, Auricular point acupressure, Laparoscopic cholecystectomy, Postoperative gastrointestinal dysfunction, Time to first passage of flatus Background Gastrointestinal dysfunction is a common complication of abdominal surgery; its main symptoms include delayed flatus and defecation, abdominal distention, abdominal pain, nausea, and vomiting.

Therefore, promoting rapid recovery from gastrointestinal function has become integral to postoperative rehabilitation [ 1 ]. Gastric motility typically recovers within 24—48 h after surgery, whereas colonic motility is generally restored within 48—72 h [ 2 ].

Thus, it often takes 2—3 days for the patient to recover from gastrointestinal dysfunction. Postoperative gastrointestinal dysfunction is usually treated using alvimopan; however, this drug has adverse effects such as nausea and vomiting [ 3 ]. Auricular point acupressure APP may be a noninvasive physical treatment for the condition of postoperative gastronintestinal dysfunction [ 45 ].

This therapy involves stimulating sensitive points on the auricle using vaccaria seeds; the points correspond to specific organs. Preliminary results showed that the APP using vaccaria seeds on CO7 can promote the recovery of gastrointestinal motility after abdominal surgery.

As the Standard Protocol Items: The APP will be performed by specialist nurses who have more than 5 years of experience and have held intermediate professional titles.Postoperative gastrointestinal dysfunction (PGD) is a complication in participants undergoing major surgical procedures under general anesthesia (GA).

Treatment of postoperative gastrointestinal dysfunction

Opioid-induced gastrointestinal dysfunction is as high as 81% in the United States [ 2 ]. Sham feeding causes vagal cholinergic stimulation of the gastrointestinal tract and elicits the release of gastrin, pancreatic polypeptide, and neurotensin, all of which affect gastrointestinal motility.

, Further prospective, randomized controlled studies on the effect of gum chewing on postoperative bowel motility are warranted. Role of inducible nitric oxide synthase in postoperative intestinal smooth muscle dysfunction in rodents.

Gastroenterology ; – Kalff JC, Schraut WH, Simmons RL, Bauer AJ. Surgical manipulation of the gut elicits an intestinal muscularis inflammatory response resulting in postsurgical ileus.

Treatment of postoperative gastrointestinal dysfunction

Ann Surg ; – treatment of postoperative gastrointestinal dysfunction. Method: patients with postoperative gastrointestinal tumors who received treatment from department of general surgery of our hospital from June to June The effects of electroacupun- cture on postoperative gastrointestinal motility recovery in patients undergoing non-gastrointestinal abdominal surgery will be .

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Postoperative gastrointestinal dysfunction (PGD) is a complication in participants undergoing major surgical procedures under general anesthesia (GA).

Opioid-induced gastrointestinal dysfunction is as high as 81% in the United States [ 2 ].